PhD in Pharmacy, University of Paris-Saclay, France
Chemical Engineer, Ecole Centrale de Marseille, France
Master of Science in Physical Chemistry, University of Aix-Marseille III, France
Medicine & Health
School of Health Sciences
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Initially educated as a Chemical Engineer, I completed a PhD in Pharmacy (University of Paris-Saclay, France) on an academia-industry collaboration to launch a new medication against brain tumours. Since then, I have worked as both an industry and academic researcher with positions held in France, Spain and New Zealand before moving to Australia in 2014. My travels led me to collaborate with a diverse range of inspiring mentors and taught me that brilliant ideas can come from anywhere, if curiosity is encouraged.
I aim to advance pharmaceutical nanoscience and pharmacy education for the greater good, through creating and passing on knowledge for better cures. My research spans from fundamental topics through to translation into new pharmaceutical products. Especially, I have contributed to the discovery and development of new “nano-drugs” against various diseases, including new antibiotics and new anticancer treatments.
My research is supported by both industry and national funding. I publish research articles in high-impact scientific journals across diverse specialised fields including supramolecular chemistry, biophysics, pharmacology and nanoscience. I am also the author of two TED-Ed videos aimed at helping the general public understand how medicines work. I am also co-inventor of three patents reporting new medications.
I am a passionate advocate for diversity, inclusion and positive leadership. I particularly enjoy working in the lab with my team and teaching student scientists from all around the world.I am also an amateur ballerina who practices pirouettes from time to time!
Sharma D; Roy A; Dharmadana D; Valery C; Chaturvedi M; Singhvi G, 2026, 'Bridging neurotransmission and tumor biology: the emerging focus on CHRM1 in skin cancer therapy', Expert Opinion on Therapeutic Targets, 30, pp. 137 - 146, http://dx.doi.org/10.1080/14728222.2026.2626525
Journal articles | 2025
Lakic B; Beh C; Sarkar S; Yap SL; Cardoso P; Valery C; Hung A; Jones NC; Hoffmann SV; Blanch EW; Dyett B; Conn CE, 2025, 'Cubosome lipid nanocarriers for delivery of ultra-short antimicrobial peptides', Journal of Colloid and Interface Science, 677, pp. 1080 - 1097, http://dx.doi.org/10.1016/j.jcis.2024.07.232
Journal articles | 2023
Cardoso P; Appiah Danso S; Hung A; Dekiwadia C; Pradhan N; Strachan J; McDonald B; Firipis K; White JF; Aburto-Medina A; Conn CE; Valéry C, 2023, 'Rational design of potent ultrashort antimicrobial peptides with programmable assembly into nanostructured hydrogels', Frontiers in Chemistry, 10, http://dx.doi.org/10.3389/fchem.2022.1009468
Journal articles | 2023
Chaturvedi M; Raj R; Yadav SK; Srivastava T; Devi S; Dharmadana D; Valéry C; Sharma SK; Kumar D; Priya S, 2023, 'Implications of In Vitro Multi-Serine Phosphorylation of Alpha-Synuclein in Aggregation and Cytotoxicity', ACS Chemical Neuroscience, 14, pp. 3103 - 3112, http://dx.doi.org/10.1021/acschemneuro.3c00234
Journal articles | 2023
Strachan JB; Dyett B; Chan S; McDonald B; Vlahos R; Valery C; Conn CE, 2023, 'A promising new oral delivery mode for insulin using lipid-filled enteric-coated capsules', Biomaterials Advances, 148, http://dx.doi.org/10.1016/j.bioadv.2023.213368
Strachan JB; Dyett BP; Jones NC; Hoffmann SV; Valery C; Conn CE, 2021, 'Reduction of enzymatic degradation of insulin via encapsulation in a lipidic bicontinuous cubic phase', Journal of Colloid and Interface Science, 592, pp. 135 - 144, http://dx.doi.org/10.1016/j.jcis.2021.02.027
Journal articles | 2020
Dharmadana D; Adamcik J; Ryan TM; Appiah Danso S; Chong CJH; Conn CE; Reynolds NP; Mezzenga R; Valéry C, 2020, 'Human neuropeptide substance P self-Assembles into semi-flexible nanotubes that can be manipulated for nanotechnology', Nanoscale, 12, pp. 22680 - 22687, http://dx.doi.org/10.1039/d0nr05622g
Journal articles | 2020
Strachan JB; Dharmadana D; Dyett BP; Valery C; Conn CE, 2020, 'Encapsulation and controlled release of the therapeutic neuropeptides somatostatin and oxytocin from the lipidic bicontinuous cubic phase', Australian Journal of Chemistry, 73, pp. 1042 - 1050, http://dx.doi.org/10.1071/CH19573
Journal articles | 2020
Strachan JB; Dyett BP; Nasa Z; Valery C; Conn CE, 2020, 'Toxicity and cellular uptake of lipid nanoparticles of different structure and composition', Journal of Colloid and Interface Science, 576, pp. 241 - 251, http://dx.doi.org/10.1016/j.jcis.2020.05.002
Journal articles | 2020
Suzuki H; Mahapatra D; Board AJ; Steel PJ; Dyer JM; Gerrard JA; Dobson RCJ; Valéry C, 2020, 'Sub-Ångstrom structure of collagen model peptide (GPO)10 shows a hydrated triple helix with pitch variation and two proline ring conformations', Food Chemistry, 319, http://dx.doi.org/10.1016/j.foodchem.2020.126598
Journal articles | 2019
Dharmadana D; Reynolds NP; Conn CE; Valéry C, 2019, 'PH-Dependent self-assembly of human neuropeptide hormone gnrh into functional amyloid nanofibrils and hexagonal phases', ACS Applied Bio Materials, 2, pp. 3601 - 3606, http://dx.doi.org/10.1021/acsabm.9b00468
Journal articles | 2019
Glossop HD; De Zoysa GH; Hemar Y; Cardoso P; Wang K; Lu J; Valéry C; Sarojini V, 2019, 'Battacin-Inspired Ultrashort Peptides: Nanostructure Analysis and Antimicrobial Activity', Biomacromolecules, 20, pp. 2515 - 2529, http://dx.doi.org/10.1021/acs.biomac.9b00291
Journal articles | 2018
Dharmadana D; Reynolds NP; Dekiwadia C; Conn CE; Valéry C, 2018, 'Heparin assisted assembly of somatostatin amyloid nanofibrils results in disordered precipitates by hindrance of protofilaments interactions', Nanoscale, 10, pp. 18195 - 18204, http://dx.doi.org/10.1039/c8nr02159g
Journal articles | 2018
Rai U; Thrimawithana TR; Dharmadana D; Valery C; Young SA, 2018, 'Release kinetics of somatostatin from self-assembled nanostructured hydrogels', Peptide Science, 110, http://dx.doi.org/10.1002/bip.23085
Journal articles | 2017
Dharmadana D; Reynolds NP; Conn CE; Valéry C, 2017, 'Molecular interactions of amyloid nanofibrils with biological aggregation modifiers: Implications for cytotoxicity mechanisms and biomaterial design', Interface Focus, 7, http://dx.doi.org/10.1098/rsfs.2016.0160
Journal articles | 2017
Rugno CM; Graan J; Hanna P; Kankanamge OP; Sharifi Z; Valery C; Thrimawithana TR, 2017, 'Stability of warfarin sodium tablets repackaged in dose administration aids', Journal of Pharmacy Practice and Research, 47, pp. 457 - 462, http://dx.doi.org/10.1002/jppr.1332
Rai U; Thrimawithana TR; Valery C; Young SA, 2015, 'Therapeutic uses of somatostatin and its analogues: Current view and potential applications', Pharmacology and Therapeutics, 152, pp. 98 - 110, http://dx.doi.org/10.1016/j.pharmthera.2015.05.007
Journal articles | 2015
Valéry C; Deville-Foillard S; Lefebvre C; Taberner N; Legrand P; Meneau F; Meriadec C; Delvaux C; Bizien T; Kasotakis E; Lopez-Iglesias C; Gall A; Bressanelli S; Le Du MH; Paternostre M; Artzner F, 2015, 'Atomic view of the histidine environment stabilizing higher-pH conformations of pH-dependent proteins', Nature Communications, 6, http://dx.doi.org/10.1038/ncomms8771
Journal articles | 2014
Kaur M; Healy J; Vasudevamurthy M; Lassé M; Puskar L; Tobin MJ; Valery C; Gerrard JA; Sasso L, 2014, 'Stability and cytotoxicity of crystallin amyloid nanofibrils', Nanoscale, 6, pp. 13169 - 13178, http://dx.doi.org/10.1039/c4nr04624b
Journal articles | 2014
Phillips AJ; Littlejohn J; Yewdall NA; Zhu T; Valéry C; Pearce FG; Mitra AK; Radjainia M; Gerrard JA, 2014, 'Peroxiredoxin is a versatile self-assembling tecton for protein nanotechnology', Biomacromolecules, 15, pp. 1871 - 1881, http://dx.doi.org/10.1021/bm500261u
Journal articles | 2013
Gobeaux F; Fay N; Tarabout C; Meneau F; Mériadec C; Delvaux C; Cintrat JC; Valéry C; Artzner F; Paternostre M, 2013, 'Experimental observation of double-walled peptide nanotubes and monodispersity modeling of the number of walls', Langmuir, 29, pp. 2739 - 2745, http://dx.doi.org/10.1021/la304862f
Journal articles | 2013
Valéry C; Pandey R; Gerrard JA, 2013, 'Protein β-interfaces as a generic source of native peptide tectons', Chemical Communications, 49, pp. 2825 - 2827, http://dx.doi.org/10.1039/c3cc39052g
Journal articles | 2013
Van Grondelle W; Lecomte S; Lopez-Iglesias C; Manero JM; Cherif-Cheikh R; Paternostre M; Valéry C, 2013, 'Lamination and spherulite-like compaction of a hormone's native amyloid-like nanofibrils: Spectroscopic insights into key interactions', Faraday Discussions, 166, pp. 163 - 180, http://dx.doi.org/10.1039/c3fd00054k
Journal articles | 2012
Gobeaux F; Fay N; Tarabout C; Mériadec C; Meneau F; Ligeti M; Buisson DA; Cintrat JC; Nguyen KMH; Perrin L; Valéry C; Artzner F; Paternostre M, 2012, 'Structural role of counterions adsorbed on self-assembled peptide nanotubes', Journal of the American Chemical Society, 134, pp. 723 - 733, http://dx.doi.org/10.1021/ja210299g
Journal articles | 2011
Tarabout C; Roux S; Gobeaux F; Fay N; Pouget E; Meriadec C; Ligeti M; Thomas D; IJsselstijn M; Besselievre F; Buisson DA; Verbavatz JM; Petitjean M; Valéry C; Perrin L; Rousseau B; Artzner F; Paternostre M; Cintrat JC, 2011, 'Control of peptide nanotube diameter by chemical modifications of an aromatic residue involved in a single close contact', Proceedings of the National Academy of Sciences of the United States of America, 108, pp. 7679 - 7684, http://dx.doi.org/10.1073/pnas.1017343108
Journal articles | 2011
Valéry C; Artzner F; Paternostre M, 2011, 'Peptide nanotubes: Molecular organisations, self-assembly mechanisms and applications', Soft Matter, 7, pp. 9583 - 9594, http://dx.doi.org/10.1039/c1sm05698k
Journal articles | 2010
Pouget E; Fay N; Dujardin E; Jamin N; Berthault P; Perrin L; Pandit A; Rose T; Valéry C; Thomas D; Paternostre M; Artzner F, 2010, 'Elucidation of the self-assembly pathway of lanreotide octapeptide into β-sheet nanotubes: Role of two stable intermediates', Journal of the American Chemical Society, 132, pp. 4230 - 4241, http://dx.doi.org/10.1021/ja9088023
Journal articles | 2008
Pandit A; Fay N; Bordes L; Valéry C; Cherif-Cheikh R; Robert B; Artzner F; Paternostre M, 2008, 'Self-assembly of the octapeptide lanreotide and lanreotide-based derivatives: The role of the aromatic residues', Journal of Peptide Science, 14, pp. 66 - 75, http://dx.doi.org/10.1002/psc.913
Journal articles | 2008
Valéry C; Pouget E; Pandit A; Verbavatz JM; Bordes L; Boisde I; Cherif-Cheikh R; Artzner F; Paternostre M, 2008, 'Molecular origin of the self-assembly of lanreotide into nanotubes: A mutational approach', Biophysical Journal, 94, pp. 1782 - 1795, http://dx.doi.org/10.1529/biophysj.107.108175
Journal articles | 2007
Grondelle WV; Iglesias CL; Coll E; Artzner F; Paternostre M; Lacombe F; Cardus M; Martinez G; Montes M; Cherif-Cheikh R; Valéry C, 2007, 'Spontaneous fibrillation of the native neuropeptide hormone Somatostatin-14', Journal of Structural Biology, 160, pp. 211 - 223, http://dx.doi.org/10.1016/j.jsb.2007.08.006
Journal articles | 2007
Pouget E; Dujardin E; Cavalier A; Moreac A; Valéry C; Marchi-Artzner V; Weiss T; Renault A; Paternostre M; Artzner F, 2007, 'Hierarchical architectures by synergy between dynamical template self-assembly and biomineralization', Nature Materials, 6, pp. 434 - 439, http://dx.doi.org/10.1038/nmat1912
Journal articles | 2004
Valéry C; Artzner F; Robert B; Gulick T; Keller G; Grabielle-Madelmont C; Torres ML; Cherif-Cheikh R; Paternostre M, 2004, 'Self-Association Process of a Peptide in Solution: From β-Sheet Filaments to Large Embedded Nanotubes', Biophysical Journal, 86, pp. 2484 - 2501, http://dx.doi.org/10.1016/S0006-3495(04)74304-0
Journal articles | 2003
Valéry C; Paternostre M; Robert B; Gulik-Krzywicki T; Narayanan T; Dedieu JC; Keller G; Torres ML; Cherif-Cheikh R; Calvo P; Artzner F, 2003, 'Biomimetic organization: Octapeptide self-assembly into nanotubes of viral capsid-like dimension', Proceedings of the National Academy of Sciences of the United States of America, 100, pp. 10258 - 10262, http://dx.doi.org/10.1073/pnas.1730609100
Public education. I collaborated with TED-ed as lesson writer for two online educational videos on pharmacology that total millions of views each:
- 'How does your body process medicine?' (2017)
- “What happens when you mix drugs?” (2019)
Women in Science. I am an advocate for diversity and inclusion in science, especially for women in science. As a member of the Homeward Bound Projects, I will travel to Antarctica in January 2025 with another 100 women scientists to raise awareness on the need for diversity in leadership and climate change actions.
My Research Supervision
I currently supervise research projects in the following areas:
peptide drug discovery, including novel antibiotics and anticancer small molecules,
protein aggregation in industry pharmaceutical formulations,
peptide-based or -templated biomaterials, including hydrogels and aerogels.
My Teaching
I am responsible for the teaching of pharmaceutics in the pharmaceutical medecine and pharmacy program.
